Indian registry in ischemic stroke- tenecteplase (IRIS- TNK)- An interim analysis

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design

BACKGROUND TNK-S2B, an innovative, randomized, seamless phase II/III trial of tenecteplase versus rt-PA for acute ischemic stroke, terminated for slow enrollment before regulatory approval of use of phase II patients in phase III. PURPOSE (1) To review the trial design and comprehensive type I error rate simulations and (2) to discuss issues raised during regulatory review, to facilitate futu...

متن کامل

Efficacy and safety of tenecteplase in diabetic and non-diabetic patients of STEMI - Indian registry data.

229 *Apollo Hospitals,Chennai; **St. Johns Medical College and Hospital, Bangalore; ***Poona Hospital and research Centre, Pune; #Jay Anand Hospital and ICCU, Thane; †Upasana Hospital, Kollam received: 09.03.2009; revised: 13.07.2009; Accepted: 13.07.2009 Introduction T has a longer half-life1 with higher fibrin selectivity,2 so that it can be administered as a single IV bolus. Efficacy and saf...

متن کامل

dysphagia in acute ischemic stroke

Introduction: Swallowing dysfunction complicates acute strokes in 25-32% of cases and directly affects patientschr('39') prognosis and recovery. Dysphagia complicates the course of acute strokes through its potential of the development of chest infection, nutritional problems, and dehydration.  Dysphagia is also an independent predictor of respiratory morbidity and mortality in acute stroke. In...

متن کامل

Pharmacological Reperfusion Therapy with Tenecteplase in 7,668 Indian Patients with ST Elevation Myocardial Infarction - A Real World Indian Experience.

Objective This real-world, observational, prescription event monitoring study was conducted to evaluate safety and efficacy of indigenous tenecteplase (TNK-tPA) in Indian patients presenting with ST elevation myocardial infarction (STEMI). Methods This is a multi-centric, observational, prescription event monitoring study. Data was collected for 7,668 patients from 1,307 investigator sites ac...

متن کامل

Thrombolysis for acute ischemic stroke by tenecteplase in the emergency department of a Moroccan hospital

INTRODUCTION Thrombolysis has radically changed the prognosis of acute ischemic stroke. Tenecteplase is a modified form of rt-PA with greater specificity for fibrin and a longer half-life. We report the experience of a Moroccan tertiary hospital in thrombolysis using Tenecteplase. METHODS We conducted an open prospective study of all patients who were treated with Tenecteplase for an acute is...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of the Neurological Sciences

سال: 2019

ISSN: 0022-510X

DOI: 10.1016/j.jns.2019.10.690